منابع مشابه
T1 Relaxation Time in Lungs of Asymptomatic Smokers
PURPOSE Interest in using T1 as a potential MRI biomarker of chronic obstructive pulmonary disease (COPD) has recently increased. Since tobacco smoking is the major risk factor for development of COPD, the aim for this study was to examine whether tobacco smoking, pack-years (PY), influenced T1 of the lung parenchyma in asymptomatic current smokers. MATERIALS AND METHODS Lung T1 measurements ...
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Introduction: Because of its spin I = 9/2, the noble gas isotope Kr possesses a nuclear electric quadrupole moment that is a source for rapid relaxation. However, its surprisingly long gas-phase T1 times of up to several hundred seconds at ambient pressure allow for Kr hyperpolarization that is 3-4 orders of magnitude above the equilibrium polarization at 9.4 T field strength [1,2]. The quadrup...
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The clinical and experimental literature has unequivocally established that mechanical ventilation with large tidal volumes is injurious to the lung. However, uncertainty about the micromechanics of injured lungs and the numerous degrees of freedom in ventilator settings leave many unanswered questions about the biophysical determinants of lung injury. In this review we focus on experimental ev...
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In rabbits, an experimental model of fat embolism was produced that simulates the course of events in the clinical situation. Small doses of fat-cell suspension (0.075 ml/kg of body weight), prepared by collagenase treatment of homologous adipose tissue, were injected intravenously. Concomitantly, hypovolemia was produced in two animal groups by either withdrawing 20 percent of the estimated bl...
متن کاملShear stress relaxation in liquids.
We show that at high densities, as the system size decreases, liquid becomes able to permanently sustain increasing internal shear stress after a constant deformation, although the other characteristic liquid properties, such as the pair distribution function and diffusion coefficient do not change under strain. The system size necessary for observation of this effect increases with the decreas...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1959
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1959.sp006179